Coming from the A1 you follow the A35 to Enschede. Take the off-ramp to Enschede West, Universiteit (ramp 26) and take a right. Follow the road for about 500m and then take the off ramp, take the 2 leftmost lanes to go left. Follow the road for 2,5 kilometers. Take a right directly after the bridge crossing the canal. Follow this road until you reach the parking lots.
From Hengelo follow the signs to Enschede, you will end up on the Enschedesestraat. When leaving Hengelo keep following the road for 2,5 kilometers. When you reach the intersection in Enschede take a right and a right immediately after. Follow the road until you reach the parking lots.
The Grolsch Veste is situated right next to the 'Kennispark' train station.
You can reach the Grolsch veste by bus by taking line 1.